Visions such as those of Ezekiel and John, describe figures with the heads of a man, lion, ox, and eagle, which just happen to match the four “Cornerstone” constellations (Ezekiel 1:10, Revelation 4:7). It is precisely these four key figures which are the most easily matched with the four principal sons of Israel because each is mentioned in the blessings. Reuben is compared to a man and to water, Judah is compared to a lion, Dan to a serpent (counterpart of the eagle), and Joseph’s two sons to the horns of the wild ox. Those link to the constellations of the Water Bearer, the Lion, the Scorpion, and the Bull, respectively (Genesis 49: 4, 9, 17; Deuteronomy 33:17). Those four sons are each also assigned to four directions (Numbers 2:3, 10, 18, 25), and those four constellations are evenly spaced around the circle, as are the four points of a compass.
– Twelve Sons, Twelve Constellations, by John P. Pratt, Meridian Magazine
The Four Living Creatures of the Bible and the Four ‘Cornerstone’ Constellations of the Zodiac